KPV is a tripeptide consisting of lysine, proline and valine, the C-terminal fragment of alpha-melanocyte-stimulating hormone, residues 11 to 13. It retains much of the parent hormone’s anti-inflammatory profile in research models while lacking its pigmentary activity, which has made it a useful tool for separating the two effects.
Research Applications
Research applications include NF-kB pathway inhibition assays, melanocortin-receptor-independent inflammatory signalling studies, intestinal epithelial cell and colitis models, cytokine expression profiling, and peptide transporter (PepT1) uptake research.
Product Specifications
- Quantity: 10mg per vial
- Form: Lyophilized powder
- Purity: ≥99% (HPLC verified)
- Sequence: Lys-Pro-Val (alpha-MSH 11-13)
- Molecular weight: ≈342.4 Da
- Storage: Store at -20°C. Reconstituted solution stable at 2-8°C for up to 14 days.
- CAS Number: 67727-97-3
⚠️ For laboratory and research use only. Not intended for human or veterinary use.
