Tesamorelin is a synthetic analogue of human growth hormone-releasing hormone, consisting of the full 44-residue GHRH sequence with a trans-3-hexenoyl group attached to the N-terminal tyrosine. That modification substantially slows enzymatic degradation while preserving receptor affinity, making it a well-characterised reference compound in GHRH research.
Research Applications
Laboratory research with tesamorelin focuses on GHRH receptor binding and downstream cAMP signalling, pituitary somatotroph culture studies, comparative analogue stability research, and adipose tissue and lipid metabolism models conducted in vitro and in animal models.
Product Specifications
- Quantity: 10mg per vial
- Form: Lyophilized powder
- Purity: ≥99% (HPLC verified)
- Sequence length: 44 amino acids
- Molecular weight: 5135.9 Da
- Storage: Store at -20°C. Reconstituted solution stable at 2-8°C for up to 14 days.
- CAS Number: 218949-48-5
⚠️ For laboratory and research use only. Not intended for human or veterinary use.
